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We offer expert laboratories of physicochemical methods of analysis a gas chromatograph with a quadrupole mass spectrometric detector «MAESTRO-αMS». Quadrupole GC-MS «MAESTRO-αMS» is in demand for targeted research (screening) and non-targeted search. In targeted studies, it is necessary to detect given target compounds in samples of various nature and origin at the level of residual amounts, for example, several picograms of the target compound in the injected 1 μl of liquid sample. Most often, targeted research is carried out in the following areas of laboratory screening: ecology, food safety, clinical monitoring, narcology, doping control, production control of various raw materials. In targeted studies, it is often required not only to confirm the presence of a compound in a sample, but also to determine the level of its content quantitatively, since both the list of target compounds and the permissible level of their presence in the sample are specified by regulatory documents. Quantitative analysis requires standards for the substances you are looking for. When conducting a non-target search, as a rule, it is required to analyze a sample of unknown composition, in other words, to find as many compounds as possible in the sample and identify (identify) each of them. Since the identification of a detected compound is carried out by comparing its experimental mass spectrum with the spectrum of a pure substance obtained under standard conditions, this task requires reference libraries of mass spectra of pure substances, as well as tools for working with mass spectra, for example: algorithms for cleaning experimental mass spectra from background and spectral noise (mass spectrum deconvolution algorithms), library search and comparison algorithms. An off-target search is called a qualitative analysis, since the researcher is primarily interested in the list of detected substances, and not in the quantitative assessment of their content in the sample. When creating MAESTRO-αMS, we took into account our own many years of experience in operating imported analogues. We have made the device inexpensive. We have made the device compact: The modern design of the device made it possible to make the MAESTRO-αMS really compact, so that the device occupies the smallest possible area on the laboratory table. The layout of the device allows you to remove the ion source on the front flange for cleaning and replacing the cathodes, if necessary. We have reduced the cost of operation: When developing the MAESTRO-αMS, we sought to increase the resistance of the device to sample matrices and use a minimum of consumable materials in order to eliminate downtime for maintenance and replacement. As a result, we have created an extremely stable ion source and a perpetual photomultiplier detector. We have created special software: Even at the first acquaintance with the software, it becomes obvious that being in the window of each button and each parameter to be changed is expedient and logical. Our software product was created for the convenience of the operator, so we implemented the necessary and eliminated the unnecessary. We used the principle of one active window, in which the operator moves sequentially step by step, performing hardware settings, setting the data collection method, subsequent processing algorithms, templates for presenting the results. MAESTRO-αMS offers a wide range of scanning modes, built-in algorithms for working with mass spectral data, convenient unloading of initial data arrays for their processing in specialized software packages, graphics export for presentations and scientific publications. You can use several libraries of mass spectra at the same time, or create your own for your typical tasks. Finally, we provide a 5-day training course for professionals who want to understand the theoretical foundations of the method and their implementation in the hardware of modern quadrupole GC/MS. The volume and depth of presentation of the material from the developers of the device is intended to lay the foundation for the effective use of «MAESTRO-αMS» in the future. Some technical characteristics of MAESTRO-αMS: • Instrumental detection limit (SIM, OFN @272 m/z ) < 10 fg; • Scan modes: scan for selected ions, full scan in a given mass range, combined scan mode; • The number of simultaneously connected libraries of mass spectra is at least 10.

The lowest cost and most compact version of the LumoTrace® Optical Imaging System manufactured by Abisens LLC for sensitive bioluminescence detection. The compactness and low price of the LumoTrace®Lite imaging system are due to the fact that it allows only bioluminescence to be recorded (older models, in addition to bioluminescence, allow fluorescence to be recorded, and are also modular, which provides them with the opportunity to upgrade). Despite its compactness and relatively low price, this model is equipped with a new highly sensitive digital camera HICMOS manufactured by Abisens LLC, which allows recording ultra-small amounts of phosphor both in laboratory animals in vivo and in vitro experiments. The device is an indispensable tool for conducting preclinical studies on the way to the introduction of advanced drugs, in the implementation of non-invasive monitoring of the development of socially significant diseases, monitoring the effectiveness of immuno- and gene therapy,

At the Scientific Research Center of the Russian Academy of Sciences, the technology of acousto-optic filtration of optical radiation is used to create a wide class of optical devices that are successfully used, for example, in biomedicine to diagnose various diseases (including oncology), in agriculture to diagnose the condition of plants, during non-destructive testing of complex technical objects and in solving other tasks. Acousto-optics has a number of important advantages over other technologies for obtaining spectral information: - the ability to create imaging devices without spatial scanning, since the acousto-optic filter is a software-controlled tunable light filter; - the compact modular design allows the acousto-optic filter to be integrated into the optical circuit of most imaging devices, which expands their analytical capabilities; - spectrum scanning is carried out by means of an electrical signal, without mechanical scanning; - fast arbitrary spectral addressing causes high shooting speed and the absence of redundant information; - software management. The key element of the presented device – an acousto–optic filter - is being developed at the Scientific Research Center of the UP RAS on the basis of original calculation methods. The manufacture of acousto-optic filters, optical and mechanical components, as well as the assembly, tuning, and calibration of such devices is also carried out at the Scientific Research Center of the UP RAS.

Scanning Probe Microscopy In air and in liquid: AFM (contact + semi-contact + non-contact) / Lateral Force Microscopy/ Phase Mapping/ Force Modulation/ Adhesive Force Mapping/ Lithographs: AFM (Power) Only in air: STM/MSM/ESM/SEM/ Kelvin Probe Method/ Display of Spreading Resistance/ AFAM (on demand)/Lithographs: AFM (Current), STM/.

Designed to perform two functions: - measurements of the air flow rate (wind); - alarm when the measured parameter exceeds the set value.

Designed to perform two functions: - measurements of the air flow rate (wind); - alarm when the measured parameter exceeds the set value.

This laboratory equipment for research purposes allows you to obtain fluorescent images of micro-preparations on slides or in a 96-well tablet in automatic scanning mode. It has high performance and allows you to automate microscopic studies to save researchers time when routinely obtaining a large number of fluorescent images.

The highly sensitive HICMOS digital camera manufactured by Abisens LLC is used to register weak light signals, including bioluminescence, in real time, with a photon counting function and visualization of the signal accumulation process in real time (you do not need to wait for the end of the exposure time to see the light signal accumulated by this moment). It is used as a component of high-tech laboratory equipment for scientific research, including installation in the fluorescence and bioluminescence imaging System in LumoTrace® biological samples manufactured by Abisens LLC.

It allows the generation of lipid particles for their subsequent use in the creation of RNA vaccines. The Russian equivalent of Nanoassembler systems.

Technical specifications: Operating spectral range, nm from 190 to 360 Limits of permissible absolute error of wavelength setting, nm ± 5 Detection limit of anthracene (wavelength 252 nm), ng/cm3, no more than 1 The limit of the permissible value of the relative mean square deviation of the output signal (n =5), % of the retention time over the peak area of 1.5 2 Limits of the permissible value of the relative change in the output signal (peak area) for 4 hours of continuous operation, % ± 5 Overall dimensions (LxWxH), mm, no more: 270x420x190 Weight, kg, not more than 9.5 Power consumption, V· A, not more than 50