SYNTOL

Specifications: 1. The number of flow cells is 1 pc. 2. Reading - double-ended 2x250 nucleotides. 3. Productivity - 7.5 billion nucleotides (15 million reads). 4. The analysis time is no more than 40 hours.

DNA sequencing and fragment analysis technologies are the most informative methods of DNA analysis, therefore NANOPHOR 05 devices are used to solve a wide range of tasks in personalized medicine and sanitary and epidemiological control, in criminology, animal husbandry, crop production, veterinary medicine, fisheries, quarantine and metrological services, as well as in basic scientific research. The genetic analyzer was developed and mass-produced in Russia by the consortium "Russian Genetic Technologies" as part of the Institute of Analytical Instrumentation of the Russian Academy of Sciences (St. Petersburg), the FGUP EZAN plant (Chernogolovka) and NPF Syntol LLC (Moscow). NANOPHORE 05 has registration certificate No. RNZ 2015/3474 dated March 11, 2022. Warranty service of the device: 24 months from the date of commissioning. Free training for the user on working with the device, commissioning, joint productions, as well as training in working with software. Technical and user characteristics Number of capillaries: 8 Tablet size: 96 x 0.2 ml Number of fluorescence detection channels: 7 Laser: solid-state Laser power: 110 MW Laser wavelength: 488 nm Voltage range: 0.1 - 15 kV Temperature maintenance range and accuracy: 30 - 70 °C (+/- 0.03 °C) Reading length with an accuracy of at least 99%: up to 950 nucleotides Standard fragment analysis time of up to 460 nucleotides: 34 minutes The maximum analyzed length of a DNA fragment (fragment analysis): at least 1200 nucleotides Weight: not more than 50 kg Applications: DNA sequencing by Sanger DNA fragment analysis (STR, QF-PCR, MSI, OLA, MLPA, SNaPshot, ISSR, AFLP, tRFLP) Identification of the person The genetic analyzer NANOPHORE 05 is distinguished by: - Wide dynamic range: the device demonstrates high sensitivity with a small amount of incoming material and high overload resistance with a large amount of incoming DNA. - Wide installation base: currently there are more than 250 devices installed in the most advanced laboratories in Russia, near and far abroad. Several million studies are performed annually on NANOPHORE 05 devices. - The low weight and reliability of the NANOPHORE 05 assembly make it possible to use the device for field work as part of mobile laboratories. - Prompt service and methodological support: directly from the manufacturer at all stages of interaction with the customer. A quick solution to any technical issue due to the fact that specialists from the chief designer to the assembly shop employee are located in Russia. - Regular schools on modern methods of DNA sequencing and fragment analysis. - High quality and availability of reagents: Our own production of reagents enables our customers to receive all the solutions necessary for their work from one source. Stable delivery times of NANOPHOR 05 devices, related equipment, reagents and consumables and long shelf life of reagents due to the production base in Russia. - Openness of the system: the ability to use reagents and kits from third-party manufacturers, the ability to create your own protocols.

The open system allows you to work with reagents and laboratory plastics from various manufacturers Russian-language software Modifications: - COLIBRI 24 - the ability to select from 1 to 24 samples - COLIBRI 48 - the ability to select from 1 to 48 samples - COLIBRI 96 - the ability to select from 1 to 96 samples Range of working volumes: - COLIBRI 24 - 200 – 5000 mkl - COLIBRI 48 - 30 – 1000 mkl - COLIBRI 96 - 20 – 1000 mkl A unique format of consumable plastic - 8-hole strips and combs Two built-in thermostats The accuracy of temperature maintenance is ± 1 °C Heating/cooling - up to 100 °C / up to 35 °C Universal Thermostat Tube Unit Built-in computer Ready-made allocation protocols The time of one extraction cycle is from 11 minutes Built-in bactericidal UV lamp for interior treatment

The QUBIX fluorimeter is a device for determining the concentration of biological molecules. It is designed to detect fluorescence excited in a dye that is part of the reagents for the reaction. - Measurement of fluorescence simultaneously in 8 samples - Convenient Russian-language software - The ability to measure fluorescence in a volume of 40 µl, which is important when working with samples with a small amount of DNA