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Human hepatocyte growth factor - participates in the processes of morphogenesis and regeneration, stimulation of the survival of hepatocytes, tubular cells of the kidneys, neurons.

Fibroblast growth factor-2 is a member of the fibroblast growth factor family. It has mitogenic activity against target cells, is a neurotrophic factor, participates in the regulation of angiogenesis, individual development, tissue regeneration, reproduction and pathogenesis of a number of diseases, including malignant tumors.

IL-7 is a hematopoietic growth factor that stimulates T-lymphocyte differentiation and maintains homeostasis of naive T-cells and memory T-cells. It is possible that human IL-7 is involved in the regulation of postnatal development of B-lymphocytes. IL-7 plays an important role in the development of secondary lymphoid organs.

IL-15 is a pleiotropic cytokine. It is essential for the development, survival, and activation of NK cells. Participates in the induction of cytotoxic effector cells. Acting as an interleukin-2 antagonist, IL-15 contributes to the maintenance of CD8+ T memory cells and the maintenance and survival of CD4+ and CD8+ T lymphocytes. Acts on a number of other cells.

Epidermal growth factor is a polypeptide that stimulates the differentiation and growth of epithelial cells.

Insulin-like human growth factor I is a protein from the family of insulin-like growth factors, a hormone with a pleiotropic effect, which is involved in the growth processes of cell proliferation and differentiation, promotes cell survival, maintains their functions, and has anabolic effects.

Interleukin-6 is a cytokine that is secreted in response to infection or tissue damage and induces the production of proteins of the acute phase of inflammation, stimulates hematopoiesis and the immune response.

Vascular Endothelial Growth Factor is one of the key regulators of angiogenesis. The most important role in the human body is played by a protein of the VEGF family called VEGF-A. VEGF-A is a 45 kDa glycoprotein homodimer and plays a key role in chemotaxis and angioblast differentiation, endotheliocyte (EC) proliferation, vasculogenesis, and vascular remodeling. As a result of alternative splicing or proteolytic cleavage, 4 main isoforms of VEGF-A are formed, consisting of 121, 165, 189, or 206 amino acid residues.

Vascular Endothelial Growth Factor is one of the key regulators of angiogenesis. The most important role in the human body is played by a protein of the VEGF family called VEGF-A. VEGF-A is a 45 kDa glycoprotein homodimer and plays a key role in chemotaxis and angioblast differentiation, endotheliocyte (EC) proliferation, vasculogenesis, and vascular remodeling. As a result of alternative splicing or proteolytic cleavage, 4 main isoforms of VEGF-A are formed, consisting of 121, 165, 189, or 206 amino acid residues.

Nojin is a protein involved in the development of various tissues, including bone, muscle and nerve. It is an antagonist of bone morphogenetic proteins (MBPs). Noggin has been implicated in a number of pathological conditions.

Interleukin 4 is a pleiotropic cytokine that regulates the cellular and humoral immune response and is involved in the processes of proliferation, differentiation, and activation of cells of various types. IL-4 is expressed by activated T lymphocytes, mast cells, dendritic cells, NKT cells, basophils, eosinophils. The epithelium and tumor cells are sources of IL-4 in tissues.

Thrombopoietin is a glycoprotein hormone synthesized mainly in the liver, the main physiological regulator of platelet production. Participates in the development of precursors of other blood cells. TPO and other TPO receptor agonists are promising therapeutic agents.