SajStorLab

Thrombopoietin is a glycoprotein hormone synthesized mainly in the liver, the main physiological regulator of platelet production. Participates in the development of precursors of other blood cells. TPO and other TPO receptor agonists are promising therapeutic agents.

Nojin is a protein involved in the development of various tissues, including bone, muscle and nerve. It is an antagonist of bone morphogenetic proteins (MBPs). Noggin has been implicated in a number of pathological conditions.

IL-7 is a hematopoietic growth factor that stimulates T-lymphocyte differentiation and maintains homeostasis of naive T-cells and memory T-cells. It is possible that human IL-7 is involved in the regulation of postnatal development of B-lymphocytes. IL-7 plays an important role in the development of secondary lymphoid organs.

Green fluorescent protein (GFP) isolated from the jellyfish species Aequorea Victoria, consists of 238 amino acids with a molecular weight of about 27 kDa. GFP is characterized by two absorption peaks in blue light at 395 nm (major) and 475 nm (minor) and a fluorescence peak at 498 nm in the green range. At present, the gene for this protein and proteins derived from it, glowing with different colors, is used as a luminous marker in cell and molecular biology to study protein expression in cells and living organisms in vivo. GFP also allows purification of recombinant proteins, where GFP or its derivatives are used as an affinity label.

Erythropoietin (EPO) is a cytokine (glycoprotein) that stimulates erythropoiesis.

Human Serum Albumin (HSA) is the main human plasma protein and has many physiological properties due to its unique structure.

Granulocyte-macrophage colony-stimulating factor is a hematopoietic growth factor and an immune response modulator. Human GM-CSF is a 127 amino acid monomeric protein with two glycosylation sites. The variability in glycosylation results in differences in molecular weight ranging from 14 kDa to 35 kDa. Non-glycosylated and glycosylated GM-CSF show similar activity in vitro.

Human hepatocyte growth factor - participates in the processes of morphogenesis and regeneration, stimulation of the survival of hepatocytes, tubular cells of the kidneys, neurons.

Green fluorescent protein (GFP) isolated from the jellyfish species Aequorea Victoria, consists of 238 amino acids with a molecular weight of about 27 kDa. GFP is characterized by two absorption peaks in blue light at 395 nm (major) and 475 nm (minor) and a fluorescence peak at 498 nm in the green range. At present, the gene for this protein and proteins derived from it, glowing with different colors, is used as a luminous marker in cell and molecular biology to study protein expression in cells and living organisms in vivo. GFP also allows purification of recombinant proteins, where GFP or its derivatives are used as an affinity label.

Anti-c-Myc Tag antibody - mouse monoclonal antibodies to the Myc-tag epitope corresponding to amino acid residues 410-419 (EQKLISEEDL) in the C-terminal domain of human c-Myc. These antibodies are used in immunological methods for the detection of recombinant Myc-tag proteins, as well as for the purification of proteins by affinity chromatography.

Interleukin 4 is a pleiotropic cytokine that regulates the cellular and humoral immune response and is involved in the processes of proliferation, differentiation, and activation of cells of various types. IL-4 is expressed by activated T lymphocytes, mast cells, dendritic cells, NKT cells, basophils, eosinophils. The epithelium and tumor cells are sources of IL-4 in tissues.

Vascular Endothelial Growth Factor is one of the key regulators of angiogenesis. The most important role in the human body is played by a protein of the VEGF family called VEGF-A. VEGF-A is a 45 kDa glycoprotein homodimer and plays a key role in chemotaxis and angioblast differentiation, endotheliocyte (EC) proliferation, vasculogenesis, and vascular remodeling. As a result of alternative splicing or proteolytic cleavage, 4 main isoforms of VEGF-A are formed, consisting of 121, 165, 189, or 206 amino acid residues.